Unbiased transcriptomes of resting human CD 4 + CD 45 RO + T lymphocytes

Unbiased transcriptomes of resting human CD4+CD45RO+ T lymphocytes

Gene expression profiling of cells of the immune system isolated ex vivo is a unique tool to assess gene expression in vivo. Exemplified for CD4+CD45RO+ effector/memory T helper (TE/M) lymphocytes of human peripheral blood, we have analyzed the influence of different isolation procedures and storage conditions on the gene expression profile [1], and describe a method for the generation of unbia...

CMV T Lymphocytes + , CD 8 − CD 27 + CD 45 RA Frequencies of Circulating

Enhanced CD 4 T

Regulatory Interactions between CD 45 RBhiO and CD 45 RB l ~ CD 4 + T Cells Are Important for the Balance between Protective and Pathogenic Cell - mediated Immunity

BALB/c mice infected with the intracellular protozoan Leishmania major mount a T hdper cell 2 (Th2) response that fails to control growth of the parasite and results in the development of visceral leishmaniasis. Separation of CD4 + T cells into CD45RB hgh and CD45KB l~ subsets showed that the L. major-specific Th2 cells were contained within the CD45RB I~ population as these cells produced high...

Nonregulatory ) T Cells − CD 25 + ( Regulatory ) versus CD 4 + CD 25 + CD 4 Platelet Factor 4 Differentially Modulates